The Chavez Tick Lab

- Leal-Galvan B, Kumar D, Karim S, Saelao P, Thomas DB and Oliva Chavez A (2024) A glimpse into the world of microRNAs and their putative roles in hard ticks. Front. Cell Dev. Biol. 12:1460705. doi: 10.3389/fcell.2024.1460705

- Butler LR, Singh N, Marnin L, Valencia LM, O'Neal AJ, Paz FEC, Shaw DK, Chavez ASO, Pedra JHF. The role of Rab27 in tick extracellular vesicle biogenesis and pathogen infection. Parasit Vectors. 2024 Feb 9;17(1):57. doi: 10.1186/s13071-024-06150-7. PubMed PMID: 38336752; PubMed Central PMCID: PMC10854084.

- Butler LR, Gonzalez J, Pedra JHF, Oliva Chavez AS. Tick extracellular vesicles in host skin immunity and pathogen transmission. Trends Parasitol. 2023 Oct;39(10):873-885. doi: 10.1016/j.pt.2023.07.009. Epub 2023 Aug 16. Review. PubMed PMID: 37591719; PubMed Central PMCID: PMC10528898.

- Oliva Chávez AS, Guzman Valencia S, Lynn GE, Rosario CA, Thomas DB, Johnson TL. Evaluation of the in vitro acaricidal effect of five organic compounds on the cattle fever tick Rhipicephalus (Boophilus) microplus (Acari: Ixodidae). Exp Appl Acarol. 2023 Apr;89(3-4):447-460. doi: 10.1007/s10493-023-00780-9. Epub 2023 Apr 13. PubMed PMID: 37052726; PubMed Central PMCID: PMC10167096.

- Gordon JL, Oliva Chavez AS, Martinez D, Vachiery N, Meyer DF. Possible biased virulence attenuation in the Senegal strain of Ehrlichia ruminantium by ntrX gene conversion from an inverted segmental duplication. PLoS One. 2023;18(2):e0266234. doi: 10.1371/journal.pone.0266234. eCollection 2023. PubMed PMID: 36800354; PubMed Central PMCID: PMC9937504.

- Underwood J, Harvey C, Lohstroh E, Pierce B, Chambers C, Guzman Valencia S, Oliva Chávez AS. Anaplasma phagocytophilum Transmission Activates Immune Pathways While Repressing Wound Healing in the Skin. Life (Basel). 2022 Nov 24;12(12). doi: 10.3390/life12121965. PubMed PMID: 36556330; PubMed Central PMCID: PMC9781593.

- Leal-Galvan B, Harvey C, Thomas D, Saelao P, Oliva Chavez AS. Isolation of microRNAs from Tick Ex Vivo Salivary Gland Cultures and Extracellular Vesicles. J Vis Exp. 2022 Apr 6;(182). doi: 10.3791/63618. PubMed PMID: 35467650.

- Skinner KM, Underwood J, Ghosh A, Oliva Chavez AS, Brelsfoard CL. Wolbachia Impacts Anaplasma Infection in Ixodes scapularis Tick Cells. Int J Environ Res Public Health. 2022 Jan 18;19(3). doi: 10.3390/ijerph19031051. PubMed PMID: 35162074; PubMed Central PMCID: PMC8834366.

- Park JM, Oliva Chávez AS, Shaw DK. Ticks: More Than Just a Pathogen Delivery Service. Front Cell Infect Microbiol. 2021;11:739419. doi: 10.3389/fcimb.2021.739419. eCollection 2021. PubMed PMID: 34540723; PubMed Central PMCID: PMC8440996.

- Oliva Chávez AS, Wang X, Marnin L, Archer NK, Hammond HL, Carroll EEM, Shaw DK, Tully BG, Buskirk AD, Ford SL, Butler LR, Shahi P, Morozova K, Clement CC, Lawres L, Neal AJO, Mamoun CB, Mason KL, Hobbs BE, Scoles GA, Barry EM, Sonenshine DE, Pal U, Valenzuela JG, Sztein MB, Pasetti MF, Levin ML, Kotsyfakis M, Jay SM, Huntley JF, Miller LS, Santambrogio L, Pedra JHF. Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection. Nat Commun. 2021 Jun 17;12(1):3696. doi: 10.1038/s41467-021-23900-8. PubMed PMID: 34140472; PubMed Central PMCID: PMC8211691.

- Ante VM, Farris LC, Saputra EP, Hall AJ, O'Bier NS, Oliva Chávez AS, Marconi RT, Lybecker MC, Hyde JA. The Borrelia burgdorferi Adenylate Cyclase, CyaB, Is Important for Virulence Factor Production and Mammalian Infection. Front Microbiol. 2021;12:676192. doi: 10.3389/fmicb.2021.676192. eCollection 2021. PubMed PMID: 34113333; PubMed Central PMCID: PMC8186283.

- Pham M, Underwood J, Oliva Chávez AS. Changing the Recipe: Pathogen Directed Changes in Tick Saliva Components. Int J Environ Res Public Health. 2021 Feb 12;18(4). doi: 10.3390/ijerph18041806. Review. PubMed PMID: 33673273; PubMed Central PMCID: PMC7918122.

- Quadros DG, Johnson TL, Whitney TR, Oliver JD, Oliva Chávez AS. Plant-Derived Natural Compounds for Tick Pest Control in Livestock and Wildlife: Pragmatism or Utopia?. Insects. 2020 Aug 1;11(8). doi: 10.3390/insects11080490. Review. PubMed PMID: 32752256; PubMed Central PMCID: PMC7469192.

- Chávez ASO, O'Neal AJ, Santambrogio L, Kotsyfakis M, Pedra JHF. Message in a vesicle - trans-kingdom intercommunication at the vector-host interface. J Cell Sci. 2019 Mar 18;132(6). doi: 10.1242/jcs.224212. Review. PubMed PMID: 30886004; PubMed Central PMCID: PMC6451414.

- Oliva Chávez AS, Herron MJ, Nelson CM, Felsheim RF, Oliver JD, Burkhardt NY, Kurtti TJ, Munderloh UG. Mutational analysis of gene function in the Anaplasmataceae: Challenges and perspectives. Ticks Tick Borne Dis. 2019 Feb;10(2):482-494. doi: 10.1016/j.ttbdis.2018.11.006. Epub 2018 Nov 15. PubMed PMID: 30466964; PubMed Central PMCID: PMC6342664.

- McClure Carroll EE, Wang X, Shaw DK, O'Neal AJ, Oliva Chávez AS, Brown LJ, Boradia VM, Hammond HL, Pedra JHF. p47 licenses activation of the immune deficiency pathway in the tick Ixodes scapularis. Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):205-210. doi: 10.1073/pnas.1808905116. Epub 2018 Dec 17. PubMed PMID: 30559180; PubMed Central PMCID: PMC6320499.

- McClure EE, Chávez ASO, Shaw DK, Carlyon JA, Ganta RR, Noh SM, Wood DO, Bavoil PM, Brayton KA, Martinez JJ, McBride JW, Valdivia RH, Munderloh UG, Pedra JHF. Engineering of obligate intracellular bacteria: progress, challenges and paradigms. Nat Rev Microbiol. 2017 Sep;15(9):544-558. doi: 10.1038/nrmicro.2017.59. Epub 2017 Jun 19. Review. PubMed PMID: 28626230; PubMed Central PMCID: PMC5557331.

- Oliva Chávez AS, Shaw DK, Munderloh UG, Pedra JH. Tick Humoral Responses: Marching to the Beat of a Different Drummer. Front Microbiol. 2017;8:223. doi: 10.3389/fmicb.2017.00223. eCollection 2017. Review. PubMed PMID: 28261180; PubMed Central PMCID: PMC5306392.

- Shaw DK, Wang X, Brown LJ, Chávez AS, Reif KE, Smith AA, Scott AJ, McClure EE, Boradia VM, Hammond HL, Sundberg EJ, Snyder GA, Liu L, DePonte K, Villar M, Ueti MW, de la Fuente J, Ernst RK, Pal U, Fikrig E, Pedra JH. Infection-derived lipids elicit an immune deficiency circuit in arthropods. Nat Commun. 2017 Feb 14;8:14401. doi: 10.1038/ncomms14401. PubMed PMID: 28195158; PubMed Central PMCID: PMC5316886.

- Oliva Chávez AS, Fairman JW, Felsheim RF, Nelson CM, Herron MJ, Higgins L, Burkhardt NY, Oliver JD, Markowski TW, Kurtti TJ, Edwards TE, Munderloh UG. An O-Methyltransferase Is Required for Infection of Tick Cells by Anaplasma phagocytophilum. PLoS Pathog. 2015;11(11):e1005248. doi: 10.1371/journal.ppat.1005248. eCollection 2015. PubMed PMID: 26544981; PubMed Central PMCID: PMC4636158.

- Oliver JD, Chávez AS, Felsheim RF, Kurtti TJ, Munderloh UG. An Ixodes scapularis cell line with a predominantly neuron-like phenotype. Exp Appl Acarol. 2015 Jul;66(3):427-42. doi: 10.1007/s10493-015-9908-1. Epub 2015 Apr 17. PubMed PMID: 25894426; PubMed Central PMCID: PMC4449809.

- Chávez AS, Felsheim RF, Kurtti TJ, Ku PS, Brayton KA, Munderloh UG. Expression patterns of Anaplasma marginale Msp2 variants change in response to growth in cattle, and tick cells versus mammalian cells. PLoS One. 2012;7(4):e36012. doi: 10.1371/journal.pone.0036012. Epub 2012 Apr 25. PubMed PMID: 22558307; PubMed Central PMCID: PMC3338850.

- Felsheim RF, Chávez AS, Palmer GH, Crosby L, Barbet AF, Kurtti TJ, Munderloh UG. Transformation of Anaplasma marginale. Vet Parasitol. 2010 Feb 10;167(2-4):167-74. doi: 10.1016/j.vetpar.2009.09.018. Epub 2009 Sep 20. PubMed PMID: 19837516; PubMed Central PMCID: PMC2817780.

- Baldridge GD, Burkhardt NY, Oliva AS, Kurtti TJ, Munderloh UG. Rickettsial ompB promoter regulated expression of GFPuv in transformed Rickettsia montanensis. PLoS One. 2010 Jan 29;5(1):e8965. doi: 10.1371/journal.pone.0008965. PubMed PMID: 20126457; PubMed Central PMCID: PMC2813287.

- Nelson CM, Herron MJ, Felsheim RF, Schloeder BR, Grindle SM, Chavez AO, Kurtti TJ, Munderloh UG. Whole genome transcription profiling of Anaplasma phagocytophilum in human and tick host cells by tiling array analysis. BMC Genomics. 2008 Jul 31;9:364. doi: 10.1186/1471-2164-9-364. PubMed PMID: 18671858; PubMed Central PMCID: PMC2527338.

- Baldridge GD, Kurtti TJ, Burkhardt N, Baldridge AS, Nelson CM, Oliva AS, Munderloh UG. Infection of Ixodes scapularis ticks with Rickettsia monacensis expressing green fluorescent protein: a model system. J Invertebr Pathol. 2007 Mar;94(3):163-74. doi: 10.1016/j.jip.2006.10.003. Epub 2006 Nov 27. PubMed PMID: 17125789; PubMed Central PMCID: PMC1868488.